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Effectiveness of thirteen-valent pneumococcal conjugate vaccine to prevent serotype 3 invasive pneumococcal disease in Quebec in children, Canada
The objective was to estimate PCV13 effectiveness to prevent serotype 3 invasive pneumococcal disease in children aged less than 5 years, using 2010-2018 mandatory notification and laboratory surveillance data, an indirect cohort design and multivariate logistic regression models. A total of 29 cases of serotype 3 and 290 non-vaccine serotype cases as controls were analysed. Overall vaccine effectiveness (≥1 dose) was estimated at 59% [-39% to 88%]. During the first year after the last dose effectivness was 88% [47% to 97%] whereas no protection was observed thereafter. There was no trend towards increased effectiveness ...
Source: Vaccine - July 31, 2023 Category: Allergy & Immunology Authors: Genevi ève Deceuninck Nicholas Brousseau Brigitte Lefebvre Caroline Quach Bruce Tapiero Yen-Giang Bui Micha ël Desjardins Philippe De Wals Source Type: research

Aeromedical retrievals as a measure of potentially preventable hospitalisations and cost comparison with provision of GP-led primary health care in a remote Aboriginal community
CONCLUSION: Greater access to GP-led primary health care may lead to fewer retrievals/hospital admissions for potentially preventable conditions. It is likely that some preventable condition retrievals might be avoided if full coverage with benchmarked numbers of rural generalist GPs in a GP-led primary health team was provided in remote communities. This may be cost-effective and improve patient outcomes, and should be further explored.PMID:37113051 | DOI:10.22605/RRH7676
Source: Rural Remote Health - April 28, 2023 Category: Rural Health Authors: Lara Wieland Gail Abernethy Source Type: research

Vaccine effectiveness of the 7-valent and 13-valent pneumococcal conjugate vaccines in Canada: An IMPACT study
Vaccine. 2023 Feb 14:S0264-410X(23)00130-5. doi: 10.1016/j.vaccine.2023.02.004. Online ahead of print.NO ABSTRACTPMID:36797099 | DOI:10.1016/j.vaccine.2023.02.004
Source: Vaccine - February 16, 2023 Category: Allergy & Immunology Authors: Jelena Vojicic Ana Gabriela Grajales Alejandro Cane Source Type: research

Acute otitis media in children 6 months to 2 years of age
Can Fam Physician. 2022 Aug;68(8):589-590. doi: 10.46747/cfp.6808589.ABSTRACTQUESTION: Acute otitis media (AOM) is one of the most common findings among children in our family medicine office, and we frequently see this illness during seasons with high rates of upper respiratory tract infections. With more widespread pneumococcal immunization, has the rate of AOM declined? What are the current recommendations for antibiotic treatment?ANSWER: Although rates of the infection have declined over time with better uptake of vaccines against Streptococcus pneumoniae, AOM is still prevalent in the pediatric population and may be a...
Source: Canadian Family Physician Medecin de Famille Canadien - August 12, 2022 Category: Primary Care Authors: Ran D Goldman Source Type: research

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